POLYMORPHONUCLEAR INVASION OF WOUNDED CORNEAS
نویسندگان
چکیده
منابع مشابه
Polymorphonuclear Invasion of Wounded Corneas
Polymorphonuclear invasion of the wounded rat cornea is quantitatively described. The inflammatory cells enter the wounded tissue during the 5th postoperative hour. They steadily increase in number until they reach a maximum between 24 and 36 hours and return to normal by about the 6th day. Six hour wounds are used to evaluate the influence of topically applied drugs on the polymorphonuclear in...
متن کاملAn organ culture system for study of adherence of Pseudomonas aeruginosa to normal and wounded corneas.
An organ culture system has been developed to study the adherence of Pseudomonas aeruginosa to unwounded corneas and to corneas healing after a 3 mm central epithelial debridement. The Pseudomonas strain was isolated from a human corneal ulcer; suspensions containing 1 X 10(8) colony-forming units/ml (CFU/ml) of bacteria were incubated with the corneas for the last 30 min of the 18 hr culture p...
متن کاملStem cell markers in the human posterior limbus and corneal endothelium of unwounded and wounded corneas.
PURPOSE The corneal endothelium is a monolayer of cells in the posterior cornea that is responsible for maintaining a clear cornea. Corneal endothelial cells may be induced to divide, but it has been held that they do not divide in the normal cornea of an adult human. Some studies have suggested that a stem cell population for the corneal endothelium exists. This population could give rise to m...
متن کاملConnective tissue growth factor is not necessary for haze formation in excimer laser wounded mouse corneas
We sought to determine if connective tissue growth factor (CTGF) is necessary for the formation of corneal haze after corneal injury. Mice with post-natal, tamoxifen-induced, knockout of CTGF were subjected to excimer laser phototherapeutic keratectomy (PTK) and the corneas were allowed to heal. The extent of scaring was observed in non-induced mice, heterozygotes, and full homozygous knockout ...
متن کاملDifferential expression of MT1-MMP (MMP-14) and collagenase III (MMP-13) genes in normal and wounded rat corneas.
PURPOSE Several members of the matrix metalloproteinase (MMP) group have been identified in the rat cornea during corneal wound healing. The aim of the present study was to identify additional members of the MMP gene family in the rat cornea and localize the expression of membrane type-1 matrix metalloproteinase (MT1-MMP; MMP-14) and collagenase III (MMP-13) in normal and wounded corneas. MET...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1957
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.105.2.141